Cheat Engine

[Lyfa]

Please state your reasons.

[InternetIsSeriousBusiness]

Trend Micro, for websites, and Kasperrsky if you download a lot.

[Gypsy++]

Eset Smart Security + Malwarebytes' Anti-Malware is the best combo. Stand alone, I'd have to say COMODO, Norman.
The best FREE AV's are:

AVG
Microsoft Security Essentials
Anti-Vir

[PUSHEAX_PUSHEAX]

NOD32, I ran my Spyeye on NVT it was the only AV to detect it as Spyeye, I tested my other IRC botnet bin's on it, and they too were detected by NOD32

If you don't know what Spyeye is google it btw.

[Notepad]

Kaspersky Internet Security-Amazing feature called 'Application Control', very lightweight (3.196k), comes with built in sandbox.

I'd suggest having SAS and Malwarebytes as on-demand scanners with any AV you use.

[Gypsy++]

I don't like Kaspersky, it's really heavy on resources, as Norton is too. I guess if you want 100-200MB of ram chewed up by an AV, go ahead. I think it mostly comes down to personal experiences and preference.

[Shota]

From best to worse
Common Sense
MSE -
NOD -
Install Gentoo
-
-
-
Avast!
Kaspersky ( honestly they gone shitwire now)
AVG








Norton- is like trying to place Space Quest without dying

[Notepad]

[noko_112]

I hate how Norman reacts when it find some of the "viruses" i have. I have to manually go into the exception list and add every single item, instead of a simple ignore button.

[GG]

ESET NOD32 Anti-virus.
Never fails me. Malwarebytes as well.
And Soybot S&D's TeaTimer monitors the registry.

With all three, you will never become infected.

EDIT:
Teatimer uses ~130mb of RAM.
ESET uses ~60mb (it scans everything in the background).